Doctor Octopus is back! He's assembled a new Sinister Six - and if you think he's thought big in the past, think again. But what Doc Ock doesn't know is that the Vulture has a sextet of his own: the Savage Six! Brace yourself for all-out war between two of the greatest villains in the Marvel Universe - and the only person they hate more than each other is Spider-Man! Spidey's in deep trouble with the toughest battle he's ever faced and a deadly dozen of his fiercest foes out for blood! AMAZING SPIDER-MAN scribe Nick Spencer and the legendary Artist Mark Bagley team up for an epic story guaranteed to shock readers!

Collects Sinister War (2021) #1-4.